abstract：:Uptake of 5-hydroxytryptamine (5-HT) by adult and fetal rabbit's ileum was studied. The adult myenteric plexus accumulated tritium when incubated with tritiated 5-HT. However, in addition to labeled 5-HT, tritiated 5-hydroxyindole acetic acid and, when monoamine oxidase (MAO) was inhibited, 5-HT-o-glucuronide were fou...

journal_title：Brain research

authors： Rothman TP,Ross LL,Gershon MD

更新日期：1976-10-22 00:00:00

abstract：:Results of the preceding paper32 suggest that bulbo-pontine respiration related units (RRU) could be classed into 4 populations according to the relation of their peak firing frequency to the respiratory cycle: one inspiratory (I) and 3 expiratory (E) (early, mid and late). A further study of their spatial distributio...

journal_title：Brain research

authors： Vibert JF,Bertrand F,Denavit-Saubié M,Hugelin A

更新日期：1976-09-17 00:00:00

abstract：:Chemical synaptic transmission was studied with microelectrode techniques in isolated frog cerebella maintained in vitro. Purkinje cell (PC) EPSPs, elicited by selective monosynaptic electrical stimulation of both the parallel fiber (PF) and climbing fiber (CF) inputs, could be inverted by depolarizing (outward) curre...

journal_title：Brain research

authors： Hackett JT

更新日期：1976-09-10 00:00:00

abstract：:Conditions for the stimulation of taurine release by illumination or increased K+ concentrations were established. The effect of Mg2+, ruthenium red and verapamil on taurine release induced by both procedures was compared. All these agents antagonize Ca2+-dependent release of neurotransmitters. Illumination-induced re...

journal_title：Brain research

authors： López-Colomé A,Erlij D,Pasantes-Morales H

更新日期：1976-09-03 00:00:00

abstract：:The periodicity of the myelin sheath in glutaraldehyde carbohydrazide (GACH) embedded tissues from three 10-day-old and two 43-day-old mice was investigated with the electron microscope. The mean repeat period and number of repeats per fiber was measured in 31-89 fibers in the trapezoid bodies, olfactory tract and sci...

journal_title：Brain research

authors： Hedley-Whyte ET,Kirschner DA

更新日期：1976-09-03 00:00:00

abstract：:(1) The levels of glycolytic intermediates in the brain tissue of 15-day-old homozygous and heterozygous Gunn rats were determined with or without novobiocin treatment in vivo, and the inhibitory effects of bilirubin on the glycolytic activity and the key glycolytic enzyme activities were investigated in vitro. (2) t...

journal_title：Brain research

authors： Katoh-Semba R

更新日期：1976-08-27 00:00:00

abstract：:The cortical afferents from individual laminae of the dorsal lateral geniculate nucleus (LGN) were studied using both light and electron microscope autoradiography. In area 17, the A geniculate laminae (A and A1) had two main bands of projection, one extending from the bottom of IVc to the deepest cells in layer III, ...

journal_title：Brain research

authors： LeVay S,Gilbert CD

更新日期：1976-08-20 00:00:00

abstract：:In this study intracellular recording techniques were used to study the synaptic events related to phase-locking of cochlear nucleus cells to low frequency stimuli. A variable degree of phase-locking was noted even with units of the same low characteristic frequency. With low frequency phase-locking units an excitator...

journal_title：Brain research

authors： Britt RH

更新日期：1976-08-13 00:00:00

abstract：:Choline uptake and ecto-cholinesterase activities have been measured in intact astroblast and neuroblast cultures. The data show that choline uptake is dependent upon the ionic composition of the culture medium and is sensitive to metabolic inhibitors. However, the high concentrations of the inhibitors necessary for t...

journal_title：Brain research

authors： Massarelli R,Stefanovic V,Mandel P

更新日期：1976-08-06 00:00:00

abstract：:Patches of transnueronal degeneration were produced in the lateral geniculate nucleus (LGN) by retinal laser burns and a tarsorrhaphy was performed in the contralateral eye of Macaca mulatta during infancy. The adverse effect of unilateral visual deprivation on geniculate cell growth was absent in those portions of de...

journal_title：Brain research

authors： Von Noorden GK,Crawford ML,Middle-Ditch PR

更新日期：1976-07-30 00:00:00

abstract：:Visuomotor behavior and pattern discrimination were studied in a group of cats raised with one eye closed by eyelid suturing 7-10 days after birth. At the age of 8-10 months the animals were forced to use their deprived eye by reversal of eye closure (closing the normal eye and opening the deprived one). Visuomotor be...

journal_title：Brain research

authors： Hof-Van Duin JV

更新日期：1976-07-30 00:00:00

abstract：:A study was made of the release of excitatory, inhibitory and other amino acids from epileptic foci induced in the sensorimotor cortex of rats by cobalt implantation. A new in vivo superfusion method was employed which gives free movement to the animals and allows study over periods of days and weeks. Most amino acids...

journal_title：Brain research

authors： Dodd PR,Bradford HF

更新日期：1976-07-30 00:00:00

abstract：:The short term effects of spinal cord hemisection on protein synthesis in the Cebus monkey were studied by measuring the uptake of [3H]lysine into the trichloroacetic acid (TCA) precipitable and non-precipitable fractions of spinal cord. Animals were sacrificed 3, 6, or 13 days after hemisection. Two normal animals an...

journal_title：Brain research

authors： Wells MR,Bernstein JJ

更新日期：1976-07-23 00:00:00

abstract：:Cultured cells derived from Tay-Sachs disease (TSD) fetal cerebellum were shown to accumulate GM2 ganglioside when compared with control cultures. In contrast, fibroblasts derived from TSD fetal lung do not contain GM2. GM2 was identified by thin-layer chromatography (TLC) and confirmed by gas-liquid chromatography (G...

journal_title：Brain research

authors： Hoffman LM,Amsterdam D,Schneck L

更新日期：1976-07-23 00:00:00

abstract：:The gustatory responses of the Mongolian gerbil were tested with 12 sugar alcohols. The electrophysiological effectiveness of the linear polyols as gustatory stimulants increased as the length of the carbon chain increased from 2 to 5. Six and 7 carbon acyclic polyols were no more effective than the pentitols. By comp...

journal_title：Brain research

authors： Jakinovich W Jr,Oakley B

更新日期：1976-07-16 00:00:00

abstract：:Injection of a potent, cholinergic muscarinic antagonist, [3H]3-quinuclidinyl benzilate ([3H]QNB), results in a localization of the drug to muscarinic receptors in rat brain. The distribution of these drug receptors was examined in various brain regions previously thought to contain cholinergic neurons. They were loca...

journal_title：Brain research

authors： Kuhar M,Yamamura HI

更新日期：1976-07-09 00:00:00

abstract：:The locus coeruleus of the adult albino rat is a clearly delimited nucleus in Nissl-stained preparations. It is surrounded by an extensive, relatively neuron-free neuropil which is not stained in reduced silver and Luxol fast blue preparations. Most if not all locus coeruleus neurons contain the enzyme dopamine-beta-h...

journal_title：Brain research

authors： Swanson LW

更新日期：1976-06-25 00:00:00

abstract：:This study was designed to elucidate the origin of norepinephrine (NE) measured in spinal cord following trauma. In normal cats the NE concentration at the lesion site increased 63% over control 1 h following experimentally produced blunt trauma (400 g-cm). Spinal cords of adrenalectomized cats were also traumatized, ...

journal_title：Brain research

authors： Schoultz TW,De Luca DC,Reding DL

更新日期：1976-06-11 00:00:00

abstract：:The present study has shown that after intravenous injection of [125I]NGF the time-course of appearance of radioactivity in all organs studied with the exception of sympathetic and sensory ganglia, roughly paralleled that of the blood. The highest levels were reached immediately after injection, after which the radioa...

journal_title：Brain research

authors： Stoeckel K,Guroff G,Schwab M,Thoenen H

更新日期：1976-06-11 00:00:00

abstract：:When a pair of stimuli separated by an appropriate interval is given to the right visceropleural connective of Aplysia californica the amplitude of the second EPSP elicited in cell R15 is usually smaller than the amplitude of the first EPSP. In the present paper we show that this phenomenon, synaptic depression, can b...

journal_title：Brain research

authors： Woodson PB,Schlapfer WT,Tremblay JP,Barondes SH

更新日期：1976-06-04 00:00:00

abstract：:(1) The possibility that water intake elicited by the administration of angiotensin-II to the preoptic region (POA), subfornical organ and anterior third ventricle is mediated by separate neural systems was investigated in 58 male Wistar rats using electrolytic lesion techniques. (2) Lesions of the midlateral hypothal...

journal_title：Brain research

authors： Kucharczyk J,Assaf SY,Mogenson GJ

更新日期：1976-05-28 00:00:00

abstract：:Horseradish peroxidase (HRP, 30% solution, 0.1-0.3 mul, 72 h) was injected unilaterally into the basal striatum (STR) and the dorsal ventricular ridge (DVR) of adult turtles (Chrysemys picta) in order to demonstrate the cells of origin of some afferents to these telencephalic structures. After selective STR injection,...

journal_title：Brain research

authors： Parent A

更新日期：1976-05-21 00:00:00

abstract：:The projections of serotonin-containing neurons of the midbrain raphe nuclei (nucleus raphe dorsalis, nucleus centralis superior) are studied by analysis of axonal transport of labeled amino acids. These results are correlated with regional alterations of serotonin content following midbrain raphe lesions which produc...

journal_title：Brain research

authors： Halaris AE,Jones BE,Moore RY

更新日期：1976-05-14 00:00:00

abstract：:The behavioral and physiological effects of electrical stimulation of the nucleus locus coeruleus (LC) were studied in the awake rat. LC electrodes consistently supported high rates of self-stimulation (SS). LC stimulation also inhibited spontaneous cellular discharges in the hippocampus (HPC). Both the LC-induced inh...

journal_title：Brain research

authors： Segal M,Bloom FE

更新日期：1976-05-14 00:00:00

abstract：:The effects of alpha-bungarotoxin from Bungarus multicinctus and Bungarus caeruleus were studied on three types of cholinergic response in Aplysia central neurones. These responses are the result of three distinct changes in ionic permeability: selective increases in permeabiliyt to Na, Cl and K, respectively. It was ...

journal_title：Brain research

authors： Kehoe J,Sealock R,Bon C

更新日期：1976-05-14 00:00:00

abstract：:The characteristics of dopamine adenylate cyclase in the rat striatum were first studied on homogenates of fresh tissues. In the assay conditions used, dopamine (10(-4) M) stimulated the enzyme activity by 250%. This effect was completely blocked by fluphenazine (10(-5) M; Ki=9X10(-9) M) and by phentolamine (10(-5) M;...

journal_title：Brain research

authors： Bockaert J,Premont J,Glowinski J,Thierry AM,Tassin JP

更新日期：1976-05-07 00:00:00

abstract：:The postnatal development of acetylcholinesterase (AChE, EC 3.1.1.7) and NADH-diaphorase was examined in the caudate-putamen nucleus and substantia nigra of rats ranging from 3 to 90 days in age. From 3 to 15 days post partum islands of AChE and NADH-diaphorase activity were observed in the caudate-putamen nucleus. In...

journal_title：Brain research

authors： Butcher LL,Hodge GK

更新日期：1976-04-23 00:00:00

abstract：:The activity of cerebellar Purkinje cells during controlled and passive movement of the forepaw was studied in the cat. Burst responses characteristic of activation by climbing fibers were observed in Purkinje cells in lobules Vb and Vc of the cerebellar vermis and paravermis. The climbing fiber responses followed the...

journal_title：Brain research

authors： Rushmer DS,Roberts WJ,Augter GK

更新日期：1976-04-16 00:00:00

abstract：:Habituation kinetics were found to vary considerably in different polysynaptic pathways of the brain stem in man. The exteroceptive reflex of the digastric muscle habituates markedly, even for stimuli repeated at 1-min intervals. The second component of the blink reflex habituates for intervals below about 8 sec, but ...

journal_title：Brain research

authors： Desmedt JE,Godaux E

更新日期：1976-04-16 00:00:00

abstract：:Male guinea pigs were given 3 tests for sexual behavior. Animals that never ejaculated were classified as low activity (LA), animals that ejaculated on one test were classified as medium activity (MA), and animals that ejaculated on two or more tests were classified as high activity (HA). Subsequently, animals from ea...

journal_title：Brain research

authors： Harding CF,Feder HH

更新日期：1976-03-19 00:00:00

abstract：:Two monkeys were trained to perform 3 kinds of spatial tasks (right-left DR, up-down DR, and conditional position discrimination with delay). In the conditional position task, the animal was required to respond to the right (left) choice key when the cue had been presented on the upper (lower) position. Single unit ac...

journal_title：Brain research

authors： Niki H,Watanabe M

更新日期：1976-03-19 00:00:00

abstract：:An extensive mapping of the caudate-putamen in rat for intracranial self-stimulation (ICS) site was undertaken to provide addtional support for the role of dopamine in brain-stimulation reward. Eight-seven per cent of the placements in the neostriatum supported ICS, with self-stimulation rates greater than 250/15 min ...

journal_title：Brain research

authors： Phillips AG,Carter DA,Fibiger HC

更新日期：1976-03-12 00:00:00

abstract：:Ouabain (5 X 10(-4) M) induced a 6-fold increase in intracellular Na+ and a 65% loss of cellular K+ in C6 glial cells which was accompanied by a 12 mV decrease in the resting membrane potential. Following ouabain washout intracellular ion concentrations and the membrane potential returned to control levels suggesting...

journal_title：Brain research

authors： Kukes G,De Vellis J,Elul R

更新日期：1976-03-05 00:00:00

abstract：:The drug 6-hydroxydopamine (6-OHDA) has been reported to reduce hypothalamic norepinephrine (NE) content after administration into the lateral ventricle without altering the dopamine content of tubero-infundibular neurons. Serum prolactin levels in male rats injected with 2 X 250 mug 6-OHDA were significantly higher t...

journal_title：Brain research

authors： Fenske M,Wuttke W

更新日期：1976-03-05 00:00:00

abstract：:The periaqueductal gray was shown to be an important component of morphine analgesia and tolerance. Two-way analgesic cross tolerance was obtained between systemic and intracerebral morphine administrations when the intracerebral site was the periaqueductal gray. Rats were pretreated with intraperitoneal morphine and ...

journal_title：Brain research

authors： Jacquet YF,Lajtha A

更新日期：1976-02-27 00:00:00

abstract：:The protein composition of subcellular fractions of the cerebella of normal and weaver, staggerer and nervous mutant mice and of X-irradiated rats are studied by polyacrylamide gel electrophoresis in sodium dodecyl sulphate. The patterns observed are compared with those of granular and Purkinje cells purified from rat...

journal_title：Brain research

authors： Mallet J,Huchet M,Pougeois R,Changeux JP

更新日期：1976-02-20 00:00:00

abstract：:Male laboratory rats were raised in two colonies, each of 27 rats, and then given intraventricular injections of the norepinephrine neurotoxin 6-hydroxydopamine (6-OHDA) or the serotonin neurotoxin 5,6-dihydroxytryptamine (5,6-DHT) or saline. They were then returned to their enclosure and behavior during the next 50 d...

journal_title：Brain research

authors： Ellison G

更新日期：1976-02-13 00:00:00

abstract：:A single informon reproduces classical conditioning to compound stimuli under a wide range of conditions during reinforcement and non-reinforcement; it also reproduces simple operant conditioning. A network of 210 informons with 8400 simultaneouslly varying pathways has been simulated; it can learn to recognize handpr...

journal_title：Brain research

authors： Uttley AM

更新日期：1976-01-30 00:00:00

abstract：:The mesencephalic reticular formation (MRF) of cats anesthetized with N2O was stimulated electrically, and the effects of this stimulation on activity in the striate cortex were studied. The variations of intra- and extracellularly recorded unit activity and the changes in the extracellular potassium concentration wer...

journal_title：Brain research

authors： Singer W,Tretter F,Cynader M

更新日期：1976-01-30 00:00:00

abstract：:Experiments have been performed on pentobarbitone anesthetized or decerebrated rats. The nature of the synchronous rhythmical activity which occurs in the inferior olive following the electrophoretic or systemic administration of harmaline, harmine, dihydro-beta-erythroidine and various other compounds, is described. ...

journal_title：Brain research

authors： Headley PM,Lodge D,Duggan AW

更新日期：1976-01-23 00:00:00